Our Work

Hepatitis C Alcohol Reduction Treatment - RCT

Project Objectives

The specific aims of this five-year study are:

**Aim 1:** To implement an RCT to evaluate alcohol abstinence in an 6-month integrated hepatitis C-alcohol treatment model compared to medical provider-delivered brief alcohol counseling and referral out among HCV-infected patients who consume alcohol.

**Aim 2:** To determine differences in secondary outcomes of the intervention versus medical provider-delivered brief alcohol counseling and referral out.

**Aim 3:** To conduct a cost effectiveness analysis (CEA) of the intervention versus medical provider-delivered brief alcohol counseling and referral out.

Project Policy Impact Description

Alcohol abstinence greatly improves the liver health for HCV-infected patients by decreasing both their degree of morbidity and their mortality. If effective, our 6-month treatment model may greatly improve the health of HCV-infected patients. In addition, our intervention may help patients qualify for and adhere to HCV antiviral medication regimens, or, once cured of HCV, benefit liver health in people who have compromised livers. This study will also determine whether the 6-month treatment model or brief alcohol counseling is more cost effective.

Department & School

Health Policy, Center for
Duke Global Health Institute

Locations

Sponsors

  • NIH-National Institute on Alcohol Abuse and Alcoholism

Collaborators

  • Duke Liver Clinic
  • UNC Liver Clinic
  • Durham VA Liver Clinic

Project Status

Ongoing

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