Research News

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Improvement Still Needed in HIV Testing in High Risk Groups

October 22, 2007

Since 2000, the rates of HIV testing have remained relatively low and constant in the United States, with about one third of Americans ever having had an HIV test, and less than a quarter of the people considered at high risk for contracting the virus that causes AIDS report having been tested in the past year.

Duke Human Vaccine Institute

Duke Human Vaccine Institute Receives $7.6M Grant

October 09, 2007

The Human Vaccine Institute at Duke University Medical Center has been awarded a $7.6 million contract from the National Institute of Allergy and Infectious Diseases (NIAID) to expand its efforts to standardize and improve the quality
of a crucial blood test used in the treatment of millions of HIV patients worldwide.

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New Core for CFAR (Center for AIDS Research)

September 21, 2007

A study examining whether treatment of herpes simplex virus-2 (HSV-2) lowers risk of becoming HIV-infected among women in Tanzania resulted in no difference in HIV infections. But did the trial take into account the issues of adherence to treatment that may have skewed results? Male circumcision may reduce transmission of some sexually transmitted infections, including HIV, but does this knowledge raise the chances that a circumcised man will increase risky sexual behavior?

Confronting Neglected Diseases

Confronting Neglected Diseases

September 18, 2007

By Jeffrey Moe, PhD… In 2002 Henry Grabowski, David Ridley, and I were awarded a grant to consider the dilemma of “neglected diseases.”

Anthony So

On the Short End of Globalization

August 30, 2007

Part 2 in a series on global health. By Anthony So. In the late 1990s, one of my early missions for The Rockefeller Foundation took me to Khayelitsha, a poor township in South Africa. Its corrugated iron shacks stood in sharp contrast to the waterfront of neighboring Cape Town.

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International Researchers Uncover New Targets for HIV Vaccine

July 19, 2007

An international team of researchers has identified three gene variants in the DNA of 486 people infected with HIV that appear to have helped some of the patients fight off the virus and delay the onset of full-blown AIDS. The researchers expect the new findings to aid the search for an HIV vaccine that would work by boosting the protective effects of one or more of these genes, and help the body’s own immune system overcome an infection. It took the international genetics team, called EuroCHAVI, pooling their cohorts of carefully selected patients and using the latest in genome-wide screening technology, 18 months to discover the three genes, that together greatly increase our knowledge of why patients differ in how well they can control the virus that causes AIDS.

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