The focus of current research efforts is in defining the effects of conductive hearing impairment on the development and function of the central auditory system. The ultimate goal of this research is to understand the impact of hearing loss, such as that associated with otitis media, on the development of auditory function in children. Experiments are currently being performed in which central auditory system activity is studied using the 2-deoxyglucose method following unilateral neonatal conductive hearing loss. Future experiments will examine changes in cell structure and interneuronal connections following acute and chronic conductive hearing loss in both neonatal and adult animals.
A second research program is focused on issues related to the cochlear implant. The cochlear implant is a device which allows for electrical stimulation of the auditory nerve in profoundly deaf patients. It has previously been demonstrated in animal studies as well as in human tissue histopathology that degeneration of central auditory pathways occurs following severe damage to the inner ear. It has been suggested that the introduction of electrical stimulation via a cochlear implant may prevent or reverse some of these degenerative changes. Experiments conducted previously examined this issue in the neonatally and adult deafened rat. Tissue analysis is currently undergoing completion.
Sajisevi, M, Schulz, K, Cyr, DD, Wojdyla, D, Rosenfeld, RM, Tucci, D, and Witsell, DL. "Nonadherence to Guideline Recommendations for Tympanostomy Tube Insertion in Children Based on Mega-database Claims Analysis." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 156, no. 1 (January 2017): 87-95.
Crowson, MG, Schulz, K, and Tucci, DL. "Access to Health Care and Hearing Evaluation in US Adults." The Annals of otology, rhinology, and laryngology 125, no. 9 (September 2016): 716-721.
Emmett, SD, Tucci, DL, Bento, RF, Garcia, JM, Juman, S, Chiossone-Kerdel, JA, Liu, TJ, de Muñoz, PC, Ullauri, A, Letort, JJ, Mansilla, T, Urquijo, DP, Aparicio, ML, Gong, W, Francis, HW, and Saunders, JE. "Moving Beyond GDP: Cost Effectiveness of Cochlear Implantation and Deaf Education in Latin America." Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 37, no. 8 (September 2016): 1040-1048.
Crowson, MG, Schulz, K, and Tucci, DL. "National Utilization and Forecasting of Ototopical Antibiotics: Medicaid Data Versus "Dr. Google"." Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 37, no. 8 (September 2016): 1049-1054.
Alberg, J, Crowson, MG, and Tucci, DL. "Access to and Uptake of Cochlear Implantation Among Children in North Carolina." North Carolina medical journal 77, no. 4 (July 2016): 247-252.
Witsell, DL, Khoury, T, Schulz, KA, Stachler, R, Tucci, DL, and Wojdyla, D. "Evaluation of Compliance for Treatment of Sudden Hearing Loss: A CHEER Network Study." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 155, no. 1 (July 2016): 48-55.
Piker, EG, Schulz, K, Parham, K, Vambutas, A, Witsell, D, Tucci, D, Shin, JJ, Pynnonen, MA, Nguyen-Huynh, A, Crowson, M, Ryan, SE, Langman, A, Roberts, R, Wolfley, A, and Lee, WT. "Variation in the Use of Vestibular Diagnostic Testing for Patients Presenting to Otolaryngology Clinics with Dizziness." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 155, no. 1 (July 2016): 42-47.
Crowson, MG, Patki, A, and Tucci, DL. "A Systematic Review of Diuretics in the Medical Management of Ménière's Disease." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 154, no. 5 (May 2016): 824-834. (Review)
Crowson, MG, and Tucci, DL. "Mini Review of the Cost-Effectiveness of Unilateral Osseointegrated Implants in Adults: Possibly Cost-Effective for the Correct Indication." Audiology & neuro-otology 21, no. 2 (January 2016): 69-71.
Crowson MG, Schulz KC, Tucci DL. Provider and patient drivers of ototopical antibiotic prescription variability. Am J Otolaryngol 36:814-9, 2015.
Piker EG, Kaylie DM, Garrison D, Tucci DL. Hospital anxiety and depression scale: Factor structure, internal consistency and convergent validity in patients with dizziness. Audiology and Neurotology 20(6):394-399, 2015.
Wolever, R.Q., Price, R., Hazelton, A.G., Dmitrieva, N., Bechard, E.M., Shaffer, J.K. & Tucci, D. Complementary therapies for significant dysfunction from tinnitus: treatment review and need for integrative medicine. Evidence-Based Complementary and Alternative Medicine, Vol 2015, Article ID 931418, 8 pages. DOI:10.1155/2015/931418, 2015.
Emmett SD, Tucci DL, Smith M, Ndegwa S, Nakku D, Kaitesi M, Ibekwe T, Mulwafu W, Gong W, Francis HW, Saunders JE: GDP matters: Cost effectiveness of cochlear implantation and deaf education in Sub-Saharan Africa. Otol and Neurotol 36:1357-65, 2015.
Saunders JE, Barrs DM, Gong W, Wilson BS, Tucci DL: Cost effectiveness of childhood CI vs. deaf education in Nicaragua: A disability adjusted life year model. Otol Neurotol, 36:1349-56, 2015.
Cunningham LL, Tucci DL: Restoring synaptic connections in the inner ear after noise damage. N Engl J Med 372:181-2, 2015.
Patki A, Tucci DL: Choosing an ear for cochlear implantation: Implant the better or worse hearing ear? Laryngoscope, (Best Practices), 125:5-6, 2015.