Neurobehavioral and fMRI Research in HIV Infection and Cocaine Dependence
This study examines the independent and additive effects of HIV infection and cocaine dependence on neurobehavioral outcomes using neuropsychological testing, functional neuroimaging, and measures of behavioral risk. In this observational study of over 150 patients, we will compare outcomes across three groups of individuals: HIV-positive cocaine users, HIV-positive non drug users, and HIV-negative cocaine users. A subset of these will have a 90-minute MRI scan to examine brain structure and function. We will also examine the impact of socio-economic status on health outcomes.