Our Work

Prepared, Protected, emPowered (P3): A PrEP Adherence App for Young Men who have Sex with Men

Project Overview

P3 is a three arm, randomized-controlled trial (RCT) that will test the efficacy of P3, a novel, theory-based mobile app that utilizes game mechanics and social networking features to improve PrEP adherence, retention in PrEP clinical care and PrEP persistence among young men who have sex with men (YMSM) and trans women who have sex with men, ages 16-24. We will test the efficacy of P3 and P3 , which adds Next Step Counseling delivered by an adherence counselor through the app, against PrEP standard of care. Participants will be randomized to P3, P3 , or standard of care. A cost comparison between P3 and P3 will be conducted.


Department & School

Health Policy, Center for
Duke Global Health Institute



  • NIH-National Institute of Mental Health NIH-National Institute on Drug Abuse NIH-National Institute of Child Health and Human Development

Project Collaborators

  • UNC
  • UNC
  • UNC

Project Status


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