Using short tandem repeat analysis to examine Anopheles biting patterns and efficacy of ITNs in preventing mosquito bites in Webuye, Kenya
2016-05-15 18:01:25 - 2016-08-15 18:01:25
Despite widespread access and use of insecticide-treated bed nets (ITN) in Bungoma County in Kenya, there has been little reduction in malaria infection rates. It has been assumed that this reduced ITN efficacy is caused by the poor condition and misuse or ITNs, or mosquito resistance to the insecticide used in the ITNs. A longitudinal observational study where weekly mosquito collections using backpack aspirators (prokopacks) was performed to examine the cause of this reduced efficacy. The human DNA in the mosquito blood meals from the collected mosquitos will be analyzed via short tandem repeat analysis (STR). This data will then be used to match the blood meal to a specific household member. This data will then be statistically analyzed to ascertain which bed net factors have the highest correlation with successful mosquito feeding.