Back to People Listing
Affiliate Faculty

Joel Meyer

Associate Professor of Environmental Toxicology
Director of Graduate Studies, ENV PhD program
Nicholas School of the Environment
Environmental Sciences and Policy

(919) 613-8109
joel.meyer@duke.edu

Visit Website Download CV

Joel Meyer

Summary

Dr. Meyer studies the effects of genotoxic agents on human and wildlife health. He is interested in understanding the mechanisms by which environmental agents cause DNA damage, the molecular processes that organisms employ to protect prevent and repair DNA damage, and genetic differences that may lead to increased or decreased sensitivity to DNA damage. Mitochondrial DNA damage and repair are a particular focus. He studies DNA repair and other responses to DNA damage via PCR-based analysis of DNA damage and repair, genomic and systems biology approaches, and organismal-level responses.

Teaching

Title Number Level Semester Requirements Fulfilled
Environmental Toxicology

Study of environmental contaminants from a broad perspective encompassing biochemical, ecological, and toxicological principles and methodologies. Discussion of sources, environmental transport and transformation phenomena, accumulation in biota and ecosystems. Impacts at various levels of organization, particularly biochemical and physiological effects. Prerequisites: organic chemistry and vertebrate physiology or consent of instructor. Instructor: Di Giulio. 3 units.

Course Notes:
ENVIRON 501
Was: ENVIRON 212
UG/GRAD FALL 2014 MSC: Elective
Environmental Toxicology

Study of environmental contaminants from a broad perspective encompassing biochemical, ecological, and toxicological principles and methodologies. Discussion of sources, environmental transport and transformation phenomena, accumulation in biota and ecosystems. Impacts at various levels of organization, particularly biochemical and physiological effects. Prerequisites: organic chemistry and vertebrate physiology or consent of instructor. Instructor: Di Giulio. 3 units.

Course Notes:
ENVIRON 501
Was: ENVIRON 212
UG/GRAD FALL 2013 MSC: Elective

Recent Publications

Lewis JJ, Hollingsworth JW, Chartier R, Cooper EM, Foster WM, Gomes G, Kussin P, MacInnis J, Padhi B, Panigrahi P, Rodes C, Ryde IT, Singha A, Stapleton HM, Thornburg J, Young C, Meyer JN, Pattanayak SK*. epub. Biogas stoves reduce firewood use, household air pollution, and hospital visits in Odisha, India. View

Klionsky DJ* et al. 2016. Guidelines for the use and interpretation of assays for monitoring autophagy (2nd edition). Autophagy 12:1-222. View

Van Houten B*, Hunter SE, Meyer JN. 2016. Mitochondrial DNA damage induced autophagy, cell death, and disease. Frontiers in Bioscience 21: 42-54. View

Maurer LL, Yang X, Schindler AJ, Taggart RK, Jiang C, Hsu-Kim H, Sherwood DR, Meyer JN*. 2016. Intracellular trafficking pathways in silver nanoparticle uptake and toxicity in Caenorhabditis elegans. Nanotoxicology 10: 831—835 View

Maurer LL*, Meyer JN. 2016. A systematic review of evidence for silver nanoparticle-induced mitochondrial toxicity. Environmental Science: Nano 3: 311-322. View

González-Hunt CP, Rooney JP, Joglekar R, Anbalagan C, Ryde IT, Meyer JN*. 2016. PCR-based analysis of mitochondrial DNA copy number, mitochondrial DNA damage, and nuclear DNA damage. Current Protocols in Toxicology 67:20.11.1-20.11.25. View

Wyatt LH, Diringer SE, Rogers LA, Hsu-Kim H, Pan WKY, Meyer JN*. 2016. Antagonistic growth effects of mercury and selenium in Caenorhabditis elegans are chemical species-dependent and do not depend on internal Hg/Se ratios. Environmental Science and Technology 50: 3256-64. View

Luz AL, Godebo T, Bhatt DP, Ilkayeva OR, Maurer LL, Hirschey MD, Meyer JN*. 2016. Arsenite uncouples mitochondrial respiration and induces a Warburg-like effect in Caenorhabditis elegans. Toxicological Sciences 152: 349—362. PMCID: PMC4960910. View

Luz AL, Lagido C, Hirschey MD, Meyer JN*. 2016. In vivo determination of mitochondrial function using luciferase-expressing Caenorhabditis elegans: contribution of oxidative phosphorylation, glycolysis, and fatty acid oxidation to toxicant-induced mitochondrial dysfunction. Current Protocols in Toxicology 69:25.8.1-25.8.22. View

Santa-González GA, Gómez-Molina A, Arcos-Burgos M, Meyer JN, Camargo M*. 2016. Distinct adaptive response to repeated exposure to hydrogen peroxide associated with upregulation of DNA repair genes and cell cycle arrest. Redox Biology 9: 124-133. View

Luz AL, Meyer JN*. 2016. Effects of reduced mitochondrial DNA content on secondary mitochondrial toxicant exposure in Caenorhabditis elegans. Mitochondrion 30: 255-264. View