Ashutosh Chilkoti
Senior Associate Dean in the Pratt School of Engineering
Interim Chair of the Department of Biomedical Engineering
Alan L. Kaganov Distinguished Professor of Biomedical Engineering
Professor of Biomedical Engineering
Professor in the Department of Chemistry
Research Professor of Global Health
Professor in the Thomas Lord Department of Mechanical Engineering and Materials Science
Ashutosh Chilkoti is the Alan L. Kaganov Professor of Biomedical Engineering and Chair of the Department of Biomedical Engineering at Duke University.
My research in biomolecular engineering and biointerface science focuses on the development of new molecular tools and technologies that borrow from molecular biology, protein engineering, polymer chemistry and surface science that we then exploit for the development of applications that span the range from bioseparations, plasmonic biosensors, low-cost clinical diagnostics, and drug delivery.
Current research interests focus on biomolecular materials and biointerface science and emphasizes the development of applications that span the range from bioseparations, biosensors, biomaterials, and targeted drug delivery.
Publications
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Shapiro DM, Deshpande S, Eghtesadi SA, Zhong M, Fontes CM, Fiflis D, et al. Synthetic biomolecular condensates enhance translation from a target mRNA in living cells. Nat Chem. 2025 Mar;17(3):448–56.Varanko AK, Deshpande S, Li X, Chilkoti A. Binding Strength, Not Valency, Dictates Accumulation and Penetration of Affinity Targeted Macromolecules into Solid Tumors. Biomacromolecules. 2025 Jan;26(1):503–13.Saha S, Banskota S, Yousefpour P, Schaal JL, Zakharov N, Liu J, et al. Preclinical Development of a Genetically Engineered Albumin-Binding Nanoparticle of Paclitaxel. Small Science. 2024 Nov 1;4(11).Dai Y, Zhou Z, Yu W, Ma Y, Kim K, Rivera N, et al. Biomolecular condensates regulate cellular electrochemical equilibria. Cell. 2024 Sep;S0092-8674(24)00909-7.
See more publications at Scholars@Duke