Liping Feng has devoted her entire career to improve pregnancy outcomes through innovative research. Dr. Feng conducts both basic science/laboratory research and participates in clinical studies. Her laboratory has focused on understanding the mechanisms of preterm birth, an important cause of perinatal and neonates' mortality and morbidity. Currently, she has four lines of investigation focused on the roles of progesterone receptors, inflammation/infection, genetic variation, and environmental exposure in preterm birth. These works are translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of preterm birth.
Dr. Feng services as a director and instructor for Duke Molecular Bio Techniques Workshop. This two-credit workshop designed to train clinical fellows in basic laboratory techniques. This workshop attracts participants from around the country and is now part of the Duke Clinical Research Training Master's Program. In addition, Dr. Feng has established an international collaboration in global women's health.
Potts LC, Feng L, Seed PC, Jayes FL, Kuchibhatla M, Antczak B, Nazzal MK, *Murtha AP. (2016) Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System. Biol Reprod. View
Meng Y, Murtha AP, *Feng L. (2016). Progesterone, inflammatory cytokine (TNF-%u03B1) and oxidative stress (H2O2) regulate progesterone receptor membrane component 1 (PGRMC1) expression in fetal membrane cells. Reprod Sci. In press. View
Smrtka MP, Feng L, Murtha AP, Grotegut CA. (2016). Thrombin-Induced Inflammation in Human Decidual Cells Is Not Affected By Heparin. Reprod Sci. View
Ju R, Siddiqui, N, Garrett J, Feng L, Heit M (2016). A Validated Translation of a Survey for Measuring Incontinence Knowledge in Chinese-Speaking American Immigrants. International Urogynecology Journal. View
*Feng L, Desravines N, Nazzal MK, Pryor KP, Soderblom EJ, et al. (2016) Characterization of Progesterone Receptor Membrane Component 1 in Peripheral Blood Mononuclear Cells and Plasma during Pregnancy. Adv Mol Diag 1:109. View
*Feng L, Jayes FL, Johnson LNC, Schomberg DW, Leppert PC. (2016). Biochemical Pathways and Myometrial Cell Differentiation Leading to Nodule Formation Containing Collagen and Fibronectin. Curr Protein Pept Sci. View
*Feng L, Ransom CE, Nazzal MK, Allen TK, Kuchibhatla M, Potts LC, Seed PC, Murtha AP. (2016). The role of progesterone and a novel progesterone receptor, progesterone receptor membrane component 1 (PGRMC1), in the inflammatory response of fetal membranes to Ureaplasma parvum infection. PloS one 2016;11:e0168102. View
Wang X, *Ouyang F, Feng L, Wang X, Liu Z, Zhang J (2017). Maternal urinary Triclosan concentration in relation to maternal and neonatal thyroid hormone levels: a prospective study. Environmental Health Perspective. In press.
*Feng L, Ouyang F, Liu L, Wang X, Wang X, Li Y, Murtha AP, Shen H, Zhang J and Zhang J (2016). Urinary metabolites of organophosphate flame retardants in pregnant women in Shanghai. Journal of Environmental and public health. In press.