Liping Feng's lab employs physiological, molecular, and translational approaches to study environmental health, placental biology, fetal programming, and reproductive and maternal health. Dr. Feng has a primary appointment in the Department of Obstetrics and Gynecology of the Duke University School of Medicine and her lab utilizes a wide variety of model systems including primary human trophoblast cells, stem cells, human placental tissue, mice, rats, and rabbits to support this focus. Current projects include 1) studies of the impact of perinatal PFAS exposure on placental function and early programming of fetal development, identifying mechanistic links between altered placental function, fetal growth, and adult health, placental-fetal signaling in modulating fetal immune and brain development; 2) studies of the roles of placental molecular signals in reproduction and neurobehavioral development in offspring using placental specific knockout mouse models.