Our Work

Ebola Clinical Research Consortium

Project Objectives

Develop and implement clinical trials for Ebola virus disease (EVD)

* EVD-001 Collection of EVD survivor plasma
* EVD-002 Clinical Trial of EVD survivor plasma in EVD disease
* EVD-003 Response Adaptive Randomization Platform Trial for efficient evaluation of Ebola virus treatments

Project Outcomes

Berry SM, Petzold EA, Dull P, Thielman NM, Cunningham CK, Corey GR, McClain MT, Hoover DL, Russell J, Griffiss JM, Woods CW. A response adaptive randomization platform trial for efficient evaluation of Ebola virus treatments: A model for pandemic response. Clin Trials. 2016 Jan 14. pii: 1740774515621721. [Epub ahead of print] PMID: 26768569

Thielman NM, Cunningham CK, Woods CW, Petzold E, Sprenz M, Russell J. Ebola clinical trials: Five lessons learned and a way forward. Clin Trials. 2016 Jan 14. pii: 1740774515619897. [Epub ahead of print] No abstract available. PMID: 26768559


Department & School

Medicine: Infectious Diseases
School of Medicine



  • Bill & Melinda Gates Foundation


  • Hubert-Yeargan Center
  • Duke Pediatrics
  • UNC
  • Clinical Research Management

Project Status


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