Thomas Denny
Professor in Medicine
Research Professor of Global Health
Thomas Denny
Professor in Medicine
Research Professor of Global Health
Thomas N. Denny, MSc, M.Phil, is the Chief Operating Officer of the Duke Human Vaccine Institute (DHVI) and the Center for HIV/AIDS Vaccine Immunology (CHAVI), and a Professor of Medicine in the Department of Medicine at Duke University Medical Center. He is also an Affiliate Member of the Duke Global Health Institute. He has recently been appointed to the Duke University Fuqua School of Business Health Sector Advisory Council. Previously, he was an Associate Professor of Pathology, Laboratory Medicine and Pediatrics, Associate Professor of Preventive Medicine and Community Health and Assistant Dean for Research in Health Policy at the New Jersey Medical School, Newark, New Jersey. He has served on numerous committees for the NIH over the last two decades and currently is the principal investigator of an NIH portfolio in excess of 56 million dollars. Mr. Denny was a 2002-2003 Robert Wood Johnson Foundation Health Policy Fellow at the Institute of Medicine of the National Academies (IOM). As a fellow, he served on the US Senate Health, Education, Labor and Pensions Committee with legislation/policy responsibilities in global AIDS, bioterrorism, clinical trials/human subject protection and vaccine related-issues.
Projects
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EQAPOL (External Quality Assurance Proficiency of Laboratories)
United States
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IVQAC - Immunology Virology Quality Assessment Center
United States
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Vaccine and Treatment Evaluation Unit (VTEU)
United States
Publications
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Hurst JH, Mohan AA, Dalapati T, George IA, Aquino JN, Lugo DJ, et al. Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection. Nat Commun. 2025 Mar 10;16(1):2383.Mielke D, Tuyishime M, Kelkar NS, Wang Y, Parks R, Santra S, et al. Computationally Selected Multivalent HIV-1 Subtype C Vaccine Protects Against Heterologous SHIV Challenge. Vaccines (Basel). 2025 Feb 24;13(3).Holmes S, Li H, Shen X, Martin M, Tuck R, Chen Y, et al. Neonatal immunity associated with heterologous HIV-1 neutralizing antibody induction in SHIV-infected Rhesus Macaques. Nat Commun. 2024 Nov 27;15(1):10302.Hargarten PM, Porth CG, Berrong M, Weed D, Carper M, Denny TN, et al. Decreased variability in the site-specific results during participation in the External Quality Assurance Program Oversight Laboratory (EQAPOL) proficiency program for IFN-gamma enzyme-linked immunospot (IFN-γ ELISpot) assay. J Immunol Methods. 2024 Nov;534:113770.
See more publications at Scholars@Duke