Wendy Prudhomme O'Meara
Deputy Director, Duke Global Health Institute
Professor, Medicine and Global Health
Visiting lecturer, Moi University, Eldoret, Kenya
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Wendy Prudhomme O'Meara
Deputy Director, Duke Global Health Institute
Professor, Medicine and Global Health
Visiting lecturer, Moi University, Eldoret, Kenya
Dr. O'Meara's main areas of research expertise are malaria and implementation science. She is an Professor at Duke University Medical School in the Division of Infectious Diseases, visiting professor at Moi University, and previously served as the Co-Field Director of Research for AMPATH. She has been based full-time in Kenya since 2007.
Dr. O'Meara's team is interested in improving rational drug use for suspected malaria fevers through expanding the use of diagnostic tools in the community and in health facilities. As many as 90% of fevers that seek treatment in the formal sector receive antimalarials, and it is estimated that only 20% of those buying antimalarials over-the-counter in the retail sector actually have malaria. Such overuse poses a significant threat to the continued efficacy of first-line antimalarials. Dr. O'Meara has conducted several randomized controlled trials in western Kenya to test interventions designed to improve the use of information from malaria diagnostic testing in order to target antimalarials to those with confirmed infection. In 2005, she helped to establish the Malaria Diagnostic Centre of Excellence in Kisumu, Kenya.
Recently, she concluded a case-controlled study with colleagues at Moi University that identified the major determinants of insecticide treated bednet failure in western Kenya. Among other results, the study showed that asymptomatically infected household members may be a risk factor for children living in the same household. Current work is extending this observation by leveraging variability in key parasite genes to describe the spatial mixing of malaria infections and track generations of infections from humans to mosquitoes (collaboration with Steve Taylor's lab).
Dr. O'Meara has experience in marrying innovative spatial techniques with epidemiologic outcomes. Recent work includes an analysis of health systems factors that contribute to early childhood mortality in sub-Saharan Africa.
Projects
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Spatial Scales of Plasmodium Falciparum Generations: Implications for Elimination
Kenya
- Impact of Spatial distribution of health services on child morbidity and mortality
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Developing a rapid assessment tool to identify bottlenecks to malaria prevention for elimination
Kenya
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You Get What You Look For: Emerging Infections in a Malaria Endemic Zone
Kenya
- Impact of spatial distribution of health services on child morbidity and mortality
Publications
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Saran I, Laktabai J, Menya D, Woolsey A, Turner EL, Visser T, et al. How do malaria testing and treatment subsidies affect drug shop client expenditures? A cross-sectional analysis in Western Kenya. Bmj Open. 2022 Dec 6;12(12):e066814.Taylor SM, Korwa S, Wu A, Green CL, Freedman B, Clapp S, et al. Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled trial. Plos Med. 2022 Oct;19(10):e1004104.Woolsey AM, Simmons RA, Woldeghebriel M, Zhou Y, Ogunsola O, Laing S, et al. Correction: Incentivizing appropriate malaria case management in the private sector: a study protocol for two linked cluster randomized controlled trials to evaluate provider- and client-focused interventions in western Kenya and Lagos, Nigeria. Implement Sci. 2022 Sep 15;17(1):61.Mangeni JN, Abel L, Taylor SM, Obala A, O’Meara WP, Saran I. Experience and confidence in health technologies: evidence from malaria testing and treatment in Western Kenya. Bmc Public Health. 2022 Sep 6;22(1):1689.
See more publications at Scholars@Duke