Lim, K. K., Matchar, D. B., Chong, J. L., Yeo, W., Howe, T. S., & Koh, J. S. B. (2019). Pre-discharge prognostic factors of physical function among older adults with hip fracture surgery: a systematic review.. Osteoporos Int, 30(5), 929–938. https://doi.org/10.1007/s00198-018-04831-5
Affiliate Faculty
David Matchar
(919) 286-3399
Summary
My research relates to clinical practice improvement - from the development of clinical policies to their implementation in real world clinical settings. Most recently my major content focus has been cerebrovascular disease. Other major clinical areas in which I work include the range of disabling neurological conditions, cardiovascular disease, and cancer prevention. Notable features of my work are: (1) reliance on analytic strategies such as meta-analysis, simulation, decision analysis and cost-effectiveness analysis; (2) a balancing of methodological rigor the needs of medical professionals; and (3) dependence on interdisciplinary groups of experts.
This approach is best illustrated by the Stroke Prevention Patient Outcome Research Team (PORT), for which I served as principal investigator. Funded by the AHCPR, the PORT involved 35 investigators at 13 institutions. The Stroke PORT has been highly productive and has led to a stroke prevention project funded as a public/private partnership by the AHCPR and DuPont Pharma, the Managing Anticoagulation Services Trial (MAST). MAST is a practice improvement trial in 6 managed care organizations, focussing on optimizing anticoagulation for individuals with atrial fibrillation.
I serve as consultant in the general area of analytic strategies for clinical policy development, as well as for specific projects related to stroke (e.g., acute stroke treatment, management of atrial fibrillation, and use of carotid endarterectomy.) I have worked with AHCPR (now AHRQ), ACP, AHA, AAN, Robert Wood Johnson Foundation, NSA, WHO, and several pharmaceutical companies.
Recent Publications
Wei, W. E., Wong, C. H., Matchar, D. B., Earnest, A., Wah, W., Ong, M. E. H., & Wong, T. H. (2019). Effect of Housing Type and Neighborhood Socioeconomic Indicators on Survival After Low Falls in Older Adults.. J Am Med Dir Assoc, 20(5), 646–649. https://doi.org/10.1016/j.jamda.2018.12.016
Mao, C., Yuan, J.-Q., Lv, Y.-B., Gao, X., Yin, Z.-X., Kraus, V. B., … Shi, X.-M. (2019). Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study.. Bmc Geriatrics, 19(1). https://doi.org/10.1186/s12877-019-1109-z
Chiu, C.-T., Hayward, M. D., Chan, A., & Matchar, D. B. (2019). Educational differences in the compression of disability incidence in the United States.. Ssm Population Health, 7. https://doi.org/10.1016/j.ssmph.2018.100347
Pua, Y.-H., & Matchar, D. B. (2019). Physical Performance Predictor Measures in Older Adults With Falls-Related Emergency Department Visits.. Journal of the American Medical Directors Association. https://doi.org/10.1016/j.jamda.2018.12.005
Yeoh, Y. S., Koh, G.-H., Tan, C. S., Tu, T. M., Singh, R., Chang, H. M., … Luo, N. (2019). Health-related quality of life loss associated with first-time stroke.. Plos One, 14(1). https://doi.org/10.1371/journal.pone.0211493
Ansah, J. P., Islam, A. M., Koh, V., Ly, V., Kol, H., Matchar, D. B., … Loun, M. (2019). Systems modelling as an approach for understanding and building consensus on non-communicable diseases (NCD) management in Cambodia.. Bmc Health Services Research, 19(1). https://doi.org/10.1186/s12913-018-3830-2
Matchar, D. B., Eom, K., Duncan, P. W., Lee, M., Sim, R., Sivapragasam, N. R., … Ong, M. E. H. (2019). A Cost-Effectiveness Analysis of a Randomized Control Trial of a Tailored, Multifactorial Program to Prevent Falls Among the Community-Dwelling Elderly.. Archives of Physical Medicine and Rehabilitation, 100(1), 1–8. https://doi.org/10.1016/j.apmr.2018.07.434
Chew, S. Y., Koh, M. S., Loo, C. M., Thumboo, J., Shantakumar, S., & Matchar, D. B. (2018). Making Clinical Practice Guidelines Pragmatic: How Big Data and Real World Evidence Can Close the Gap.. Ann Acad Med Singapore, 47(12), 523–527.
Tyagi, S., Koh, G.-H., Nan, L., Tan, K. B., Hoenig, H., Matchar, D. B., … Tan, C. S. (2018). Healthcare utilization and cost trajectories post-stroke: role of caregiver and stroke factors.. Bmc Health Services Research, 18(1). https://doi.org/10.1186/s12913-018-3696-3
