David Matchar
Director, Center for Clinical Health Policy Research
Professor of Medicine
Professor of Pathology
Affiliate, Duke Global Health Institute
Appointment:
David Matchar
Director, Center for Clinical Health Policy Research
Professor of Medicine
Professor of Pathology
Affiliate, Duke Global Health Institute
My scientific contributions relate innovative use of evidence to inform clinical and public policy decision making. My early work centered on stroke prevention and treatment (questionable value of carotid testing in low risk individuals, underuse and poor quality of use of anticoagulation for stroke prevention, the value of aggressive anticoagulation monitoring including the use of patient self-testing strategies, and the unappreciated role of rehabilitation in stroke care.) In cognitive impairment, my contribution has been to clarify the role of diagnostic testing for Alzheimer’s disease, the importance of early diagnosis on planning and avoidance of unnecessary testing and evaluation. In chronic kidney disease, I have guided a series of projects aimed at developing evidence-based tailored strategies for improving conformance to guidelines.
More recently, my work has applied simulation modeling to clarify the challenges of a rapidly aging population, including future prevalence of disability and the impact of education the trajectory of prevalence, understanding the role of different forms of long-term care services in alleviating caregiver burden, and estimating health care manpower requirements under alternative models of care. This work has led to the formulation of a needs-based framework for healthcare delivery and the development, validation and application of the Simple Segmentation Tool (SST), a simplified inventory of patient-level health service needs, different combinations of which can be mapped to different appropriate means for addressing these needs. I have extended this effort from developed countries (US, Singapore, and Switzerland) to low/middle income countries (Cambodia, Thailand).
I serve as consultant in the general area of analytic strategies for clinical policy development, as well as for specific projects related to stroke (e.g., acute stroke treatment, management of atrial fibrillation, and use of carotid endarterectomy.) I have worked with AHCPR (now AHRQ), ACP, AHA, AAN, Robert Wood Johnson Foundation, NSA, WHO, and several pharmaceutical companies.
Publications
-
Koh VJW, Beadle N, Chia A, Matchar DB, Chan AW-M. "You have just got to be careful"-A Qualitative Study Disentangling Health Beliefs and Behaviors Regarding Falls Among Community-Dwelling Older Adults in Singapore. J Gerontol B Psychol Sci Soc Sci. 2025 Jun 10;80(7).Praveen AD, Jha D, Baker A, Fleps I, Björnsson P, Ellingsen LM, et al. Comparison of the time-dependent discriminatory accuracy of femoral strength and bone mineral density for predicting future hip and major osteoporotic fractures: a 16-year follow-up of the AGES-Reykjavik cohort. Osteoporos Int. 2025 May 12;Matchar D, Vashishtha R, Jing X, Sivapragasam N, Sim R, Chong JL. Development and validation of a brief assessment of normative health and health-related social needs using the Simple Segmentation Tool. BMC Health Serv Res. 2025 Feb 11;25(1):230.Koh VJW, Matchar DB, Visaria A, Lai WX, Goh JW, Poh J, et al. A co-designed conceptual model for implementing falls prevention programmes for community-dwelling older adults in Singapore: a systems thinking approach. Age Ageing. 2025 Feb 2;54(2).
See more publications at Scholars@Duke