Matthew Rubach
Associate Professor of Medicine
Associate Research Professor of Global Health
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Matthew Rubach
Associate Professor of Medicine
Associate Research Professor of Global Health
Matthew Rubach, MD is a specialist in clinical infectious diseases with medical specialty training in Pediatrics, Internal Medicine and Medical Microbiology. Since November 2015, he has been based full-time as a clinical researcher and clinician in Moshi, Tanzania where he serves as Co-Director of the Kilimanjaro Christian Medical Centre (KCMC)-Duke Health Collaboration. He conducts clinical research on causes of severe febrile illness, sepsis management, vascular pathology of severe malaria, and zoonotic disease epidemiology. In addition to clinical research, he serves as Medical Director of the laboratory that supports clinical investigation at KCMC and he provides medical care & training in the HIV clinic and Medical Ward of KCMC.
His primary appointment is Associate Professor in the Department of Medicine, Division of Infectious Diseases & International Health, with a joint appointment to the Duke Global Health Institute and an adjunct appointment at Duke-National University of Singapore Medical School’s Programme in Emerging Infectious Diseases.
Dr. Rubach holds a Bachelor of Arts from Princeton University. He received his Doctor of Medicine from the University of Arizona, and then went on to complete specialty training in a combined Internal Medicine-Pediatrics residency program at the University of Utah. He completed adult sub-specialty fellowship training in Infectious Diseases at Duke University, followed by a capstone fellowship in Clinical Pathology-Medical Microbiology at the University of Utah. He has board certification from the American Board of Pediatrics (2011-2021) and is actively maintaining his board certifications from the American Board of Internal Medicine (General Medicine and Infectious Diseases) and the American Board of Pathology (Medical Microbiology).
Projects
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Sepsis Characterization in Kilimanjaro (SICK)
Tanzania
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Viral Zoonoses and Severe Febrile Illness in northern Tanzania
Tanzania
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Investigating Febrile Deaths in Tanzania
Tanzania
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Nitric Oxide and Microvascular Dysfunction in Severe Malaria
Tanzania
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Molecular Epidemiology of Brucellosis in Northern Tanzania
Tanzania
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International Maternal Pediatric Adolescent AIDS Clinical Trials
Tanzania
Publications
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Foster MW, McMahon TJ, Ngocho JS, Kipengele AH, Violette M, Chen Y, et al. Mass Spectrometry-Based Quantification of Proteins and Post-Translational Modifications in Dried Blood: Longitudinal Sampling of Patients With Sepsis in Tanzania. Proteomics. 2025 Dec 3;e70079.Dombowsky A, Dunson DB, Madut DB, Rubach MP, Herring AH. BAYESIAN LEARNING OF CLINICALLY MEANINGFUL SEPSIS PHENOTYPES IN NORTHERN TANZANIA. Ann Appl Stat. 2025 Sep;19(3):2193–217.Madut DB, Rubach MP, Allan KJ, Thomas KM, de Glanville WA, Halliday JEB, et al. Epidemiologic and Genomic Characterization of an Outbreak of Rift Valley Fever Among Humans and Dairy Cattle in Northern Tanzania. J Infect Dis. 2025 Aug 14;232(2):298–307.Spencer SA, Yongolo NM, Simiyu IG, Sawe HR, Dark P, Gordon SB, et al. The burden of multimorbidity-associated acute hospital admissions in Malawi and Tanzania: a prospective multicentre cohort study. Lancet Glob Health. 2025 Jul;13(7):e1279–90.
See more publications at Scholars@Duke


