L Gayani Tillekeratne
L Gayani Tillekeratne
Associate Professor of Medicine
Associate Research Professor of Global Health
Gayani Tillekeratne, MD MSc is an Associate Professor in the Division of Infectious Diseases and at the Duke Global Health Institute. Her work focuses on the improving the diagnosis and management of acute respiratory tract infections globally, with the goal of improving antimicrobial use for these infections. She is co-director of the Ruhuna-Duke Centre for Infectious Diseases in Sri Lanka and works with colleagues in Southeast Asia and East Africa. She is a co-investigator in several US clinical trials for COVID-19 vaccines and therapeutics. She co-instructs a course on Infectious Disease Epidemiology in Global Settings.
Projects
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ACTIV-1 (COVID-19 therapeutic trial)
United States
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RADx-UP CDCC (COVID-19 diagnostics)
United States
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Partnership for Enhancing Antimicrobial Use in Resource-Limited Settings (PEARL)
Kenya, Sri Lanka, Tanzania
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Surveillance for severe dengue in southern Sri Lanka
Sri Lanka
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Novel Diagnostics to Improve Antimicrobial Stewardship for Acute Respiratory Tract Infections in Resource-Limited Settings
Sri Lanka
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A One Health approach to antibiotic-resistant Enterobacteriaceae in South Asia
Sri Lanka
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Antibiotic-resistant Enterobacteriaceae in community-acquired urinary tract infections, southern Sri Lanka
Sri Lanka
Publications
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Iglesias-Ussel MD, O’Grady N, Anderson J, Mitsis PG, Burke TW, Henao R, et al. A Rapid Host Response Blood Test for Bacterial/Viral Infection Discrimination Using a Portable Molecular Diagnostic Platform. Open Forum Infect Dis. 2025 Jan;12(1):ofae729.Tillekeratne LG, De Soyza W, Iglesias-Ussel MD, Olague S, Palangasinghe D, Nagahawatte A, et al. Electronic Clinical Decision Support Tools: Strategies to Improve the Management of Lower Respiratory Tract Infections in Low-Resource Settings. Am J Trop Med Hyg. 2024 Dec 4;111(6):1173–7.Kurukulasooriya MRP, Tillekeratne LG, Wijayaratne WMDGB, Bodinayake CK, Dilshan UHBY, De Silva AD, et al. Prevalence and molecular epidemiology of methicillin-resistant Staphylococcus aureus in livestock farmers, livestock, and livestock products in southern Sri Lanka: A one health approach. Infect Genet Evol. 2024 Dec;126:105693.Ko ER, Reller ME, Tillekeratne LG, Bodinayake CK, Miller C, Burke TW, et al. Host-response transcriptional biomarkers accurately discriminate bacterial and viral infections of global relevance. Sci Rep. 2023 Dec 18;13(1):22554.
See more publications at Scholars@Duke